Thursday, August 30, 2007

Alzheimer’s or Dementia Medications


What drugs are approved for Alzheimer's disease?
see link above for a NIH fact sheet.

Five drugs have been approved by the U.S. Food and Drug Administration (FDA) for treating the cognitive symptoms of Alzheimer's disease. (See box.) Reminyl, Exelon, Aricept and Cognex belong to a class of drugs known as cholinesterase inhibitors. Each acts in a different way to delay the breakdown of acetylcholine, a chemical in the brain that facilitates communication among nerve cells and is important for memory. Alzheimer's disease is associated with inadequate levels of this important neurotransmitter. Namenda acts by a different mechanism. It shields brain cells from overexposure to another neurotransmitter called glutamate, excess levels of which contribute to the death of brain cells in people with Alzheimer's.

DRUGS APPROVED FOR ALZHEIMER'S
Brand Name Generic Name When Approved More Information
Namenda® memantine 2003 Fact sheet
Razadyne, Reminyl® galantamine 2001 Fact sheet
Exelon® rivastigmine 2000 Fact sheet
Aricept® donepezil 1996 Fact sheet
*Cognex® tacrine 1993 Fact sheet

* Cognex is rarely prescribed due to serious side effects, including possible liver damage.

In general, Reminyl, Exelon and Aricept are most effective when treatment is begun in the early stages. Namenda is the only drug shown to be effective for the later stages of the disease. They have all been shown to modestly slow the progression of cognitive symptoms and reduce problematic behaviors in some people, but at least half of the people who take these drugs do not respond to them. While the overall "treatment effect" of these medications is modest, studies show that when they do work, they can make a significant difference in a person's quality of life and day-to-day functioning ("activities of daily living"). The drugs have different side effects. Some are taken once a day (Aricept), others twice a day (Exelon, Reminyl and Namenda).

Wednesday, August 22, 2007

Tuesday, August 21, 2007

Estrogen Balance


SCRUNCH!

Seven Practical and Proven Ways to Maintain Estrogen Balance

  1. Go organic ­Assures minimum exposure to toxic chemicals like pesticides and bovine growth hormones that mimic estrogen in a woman’s body.
  2. Maintain normal weight ­Fat cells actually produce and store estrogen.
  3. Eat broccoli ­Broccoli contains an estrogen-balancing chemical called indole-3-carbinol. Try to get 4 or more servings per week. If raw broccoli is too crisp for your taste, lightly steam a pot of it so that it has just a slight crunch to it; then refrigerate it and include in a daily salad. Steaming actually opens up the cell wall to release nutrients. Just don’t oversteam or microwave the broccoli, which will destroy most of its nutrients. You can also try an indole-3-carbinol supplement like BioDIM.
  4. Exercise ­A significant factor that places the odds in your favor of maintaining female health. Exercise reduces stress, improves sleep and helps excrete surplus hormones.
  5. Get to sleep by 10 pm­ The sleep hormone melatonin decreases the amount of estrogen the body produces. If you go to bed late, your melatonin levels don’t rise as high because you’re exposed to darkness for a shorter period of time.
  6. Eat foods that have a low Glycemic Index (GI)­High insulin levels trigger an increase in estrogen. Check the GI of your favorite foods at www.glycemicindex.com and aim for foods with a GI of 50 or less. To lower the GI of your entire meal, try a supplement like FenuLife.
  7. Drink water and limit consumption of alcohol­ Water keeps the liver cleansed of toxins so that it can excrete hormones efficiently. Drink an ounce for every 2 pounds of body weight. Conversely, alcohol significantly compromises the liver’s ability to metabolize estrogen.


Important Supplements for Estrogen Balance

  • Turmeric­ Regulates estrogen receptors and also enhances soy’s estrogen blocking properties.
  • Green Tea ­Important antioxidant that helps keep the immune system strong, with emphasis on benefits for women’s health issues.
  • BioDim ­Helps the body effectively metabolize estrogen with the same chemical compound found in broccoli.



"....... But I feel that as a woman of a certain age, the deck is stacked against me. A woman's metabolism typically slows down as she ages (a 2 to 8 percent decrease per decade beginning in her 30s), so that even if I ate the same amount I'd gain weight. Then the hormonal imbalances that come with menopause do their dirty work, the main culprit being the thyroid, that fickle gland that regulates how quickly cells burn calories.

During menopause the thyroid is already functioning less effectively," says Keith Berkowitz, M.D., founder of The Center for Balanced Health in New York City. "If you cut fat and carbs to extremely low levels, as dieters may be inclined to do, you can further inhibit the thyroid from functioning appropriately, in addition to inhibiting the production of sex hormones." So, though I need to eat less to lose weight, I can't each too much less or my thyroid will mess with my metabolism. No wonder I am getting fatter by the minute.

I also recently learned why my fat is in my belly. During menopause, which I am experiencing, a woman's predisposition for tummy fat becomes even more dangerous. Abdominal fat is visceral fat, the kind that's more active metabolically and can wreak more havoc by contributing to higher cholesterol, higher blood fats, and higher blood pressure. In the ongoing Iowa Women's Health Study, women with the greater amounts of tummy fat had higher rates of diabetes, heart disease, and high blood pressure. Even with a low BMI, a woman with belly fat is more likely to die early. That's bad news for somebody like me who has a belly and a high BMI. " (comment on AARP newsletter)
http://www.msnbc.msn.com/id/12919730/site/newsweek/


Fight back the bulge

Since visceral fat is buried deep in your abdomen, it may seem like a difficult target for spot reduction. As it turns out, visceral fat responds well to a regular exercise routine and a healthy diet. Targeted tummy exercises can help to firm the abdominal muscles and flatten the belly.

Exercise. Daily, moderate-intensity exercise is the best way to lose belly fat ­ when you lose weight and tone your muscles, your belly fat begins shrinking, too. In fact, you may notice that your tummy bulge is the first area to shrink when you start exercising. The amount and type of exercise you should get varies depending on your current activity level and your health goals. Talk to your doctor about the right exercise program to promote good health and specifically combat abdominal fat.

Strength training. Some research has shown that exercising with weights is effective in trimming tummy fat. Talk to your doctor about how to incorporate strength training in your exercise routine.

Healthy diet. Changing unhealthy eating habits can help fight belly fat. Read nutrition labels, and replace saturated fats with polyunsaturated fats. Increase portions of complex carbohydrates like fruits and vegetables, and reduce simple carbohydrates like white bread and refined pasta. If you need to lose weight, reduce your portion sizes and daily calorie intake.

Tone your tummy. While you can't "spot-burn" belly fat, you can firm up your abdominal muscles and get a flatter belly. Traditional sit-ups aren't the most effective way to firm your tummy, however. Instead, use these exercises to target both deeper and lower abdominal muscles:

  • Deeper abdominal muscles. Target deeper abdominal muscles by doing "abdominal hollowing" or "drawing in the belly button." First, get down on all fours. Let your tummy hang down as you take a deep breath. Let your breath out, and at the end of your exhalation, gently draw your belly button inward and upward toward your spine. You should feel a slight tightening around your waist ­ think of it as trying to squeeze through a partially closed door. Hold for 10 seconds, then rest for 10 seconds. Work up to 10 repetitions. During each effort, your spine position shouldn't change and you should breathe freely. Eventually, you'll be able to do this exercise standing up. It's so subtle, no one should be able to tell you're doing it.
  • Lower abdominal muscles. Tone your lower abdomen by doing pelvic tilts and pelvic lifts. To do a pelvic tilt, lie on your back on the floor with your knees bent. Flatten your back against the floor by tightening your abdominal muscles and bending your pelvis up slightly. Hold for 5 to 10 seconds. Repeat five times and work up to 10 to 20 repetitions. For pelvic lifts, lie on your back with your knees bent up toward your chest and your arms relaxed by your sides. Tighten your lower abdomen and lift your buttocks up off the floor, with your knees aimed toward the ceiling. Hold for 5 to 10 seconds. Repeat five times and work up to 10 to 20 repetitions.

Monday, August 13, 2007

Help!




Anxiety, more or less.


Please see a clinician if you feel that you might have anxiety or panic, getting an adequate physical assessment is essential.
  • Anxiety normally starts to peak about half an hour after you get up. Anticipate it by doing some simple breathing exercises.
  • Eat little and often – learn to watch and pay attention to what your body is saying. Even fill in a ‘body clock’ to chart mood and physicality.
  • Smoking is supposed to calm the nerves, but researchers have found evidence that it might have the opposite effect.
  • The body will have a transition at roughly 4:00am and 4:00pm – learn to nurture at those times.
  • Remember that most people have panic/anxiety attacks when they are NOT stressed and when the crisis is over.
  • Each day stop and breath several times. In breath to the count of five (tensing your whole body gradually - finishing with tensing your shoulders) and then as you exhale to the count of five let your body relax down and outwards towards the tips of the fingers and toes.
  • If you think you have a task that is worrisome -- work out the steps beforehand. Then you are “chunking" it into manageable proportions that are not as stressful.
  • If you feel like you are going to stress out.... stop, shut everything down, breath and stretch, put your hands behind your head.... then think about what you want to do and go back to it.
  • Remember, work at a task in manageable 'bites' of around twenty minutes. Then stop, do something else or look up and away from the task, before returning. This means that you are rolling WITH your attention and learning curve instead of getting stuck on the plateau.
  • When your mind wanders to something that provokes anxiety – write it down and then defer dealing with it until a specific time later in the day. Write a short phrase – not a journal! Normally come back to your short list at a time when you are distracted, for example watching television, and can look at the issues without stressing out. Do not try for solutions - let your mind percolate naturally and with a night's rest you will find things easier the next day.
  • Don't stress about sleep - rest can be enough. Let your body do the 'talking'.
  • Describe your physical sensations both to yourself and to someone who is trying to help. Feeling anxious or panicked is about the body not the mind. So validate the sensations and that means that the feelings of helplessness and hopelessness are lessened by treating this as something that will eventually be managed.
  • Eat something carbohydrate at 4:00pm with some liquid - even when you are off work
  • put hands behind head in a basket to disable chest wall muscles and calm down anxiety - several times a day. Simple chair stretching helps.
  • Change task every twenty or thirty minutes - this can mean just stop and look up and straighten your back but preferably do the hands as a basket exercise.
  • Try not to drink cold milk after 6:00pm. Warm milk releases tryptophan which is a natural ‘de-compressant’.
  • think of " anxiety " as physiological stress not paranoia/ in your head
  • at night take a shower and then stretch in the shower
  • Clench your body and breathe in to the count of five, then hold for one and breathe out for the count of five relaxing the muscles out towards your finger tips and toes. Do this several times a day.
  • SING in the car to music
  • Each night have ten minutes quiet time and DOODLE - teach the kids to do this too.... - take a half hour to unwind some time in the evening.
  • MINDFULNESS:

Mindfulness is about being in the 'now': being present in this body, at this time, doing this thing. It has a quiet, unassuming and unobtrusive nature. It is also non-judgmental and not characterized by emotional reactions. It is often linked with compassion1.

The simplest form of mindfulness, which can be practiced very easily without anyone noticing, is to focus on the breath for three inhalations and exhalations. Some people do this hourly. It involves taking in a deliberate breath and noticing the quality of the air as it enters the body through the nostrils and making its way to the lungs. Then, when exhaling, you focus on the air as it leaves your body.

It's worth taking a look at the way you breathe. Most people breathe quite shallowly, using only the top part of their lungs. For the purposes of mindfulness breathing, you should use the whole of your capacity. This means inflating the bottom part first, which can be done by allowing your belly to swell (a bit like a balloon). Next, fill the mid-section by expanding your ribs sideways. Finally fill the top part of your lungs.

If you are sitting down, you can augment this by noticing the feel of the chair underneath your buttocks and the ground on your feet.

This practice will bring you back to the present moment and is very grounding.

Another form of meditation is the Walking Meditation. This can be done alone or in company. The walking can also be described as intentional. Walking mindfully entails focussing on the breath (as described above), placing and planting the feet purposefully and intentionally and being conscious of the ground, the surroundings and staying in the present moment.

STRESS SYMPTOMS:

  • General - sweating, hot flushes or cold chills.
  • Heart- pounding heart, increased heart rate.
  • Lungs - difficulty breathing or feeling of choking, chest pain or discomfort, hyperventilation.
  • Abdomen - difficulty swallowing, nausea or abdominal distress.
  • Arms and legs - numbness or tingling sensations, muscle tension with associated aches and pains.
  • Psychological - feeling 'keyed up' or on edge, fatigue, mind going blank, difficulty sleeping.

All of the anxiety disorders have these symptoms in common. As we'll see, however, they can occur under different circumstances.

Types of Anxiety Disorder

The 'purest' anxiety disorder is known as generalized anxiety disorder (GAD). This is characterized by out-of-control stress and worry over many aspects of the individual's life. The anxiety can be 'free-floating', which means that it isn’t connected to any particular situation. It is chronic and low grade, although it can occasionally flare. People with GAD primarily have problems with sleeplessness, fatigue, muscle tension and headaches.

Panic disorder is slightly different in that sometimes, for no apparent reason, the affected individual will have a full-blown panic attack, including many of the symptoms mentioned above. In between attacks, the individual will be anxiety-free, but over time they can (understandably) develop continuing anxiety about when the next attack will occur.

Phobias are anxiety disorders which are brought on by specific, identifiable situations. When in the situation, anxiety will lead to the individual trying to escape it by any means possible.

Obsessive Compulsive Disorder consists, as its name suggests, of unpleasant and distressing obsessive thoughts linked to the individual's compelling need to perform particular actions to compensate for them in some way. An example of an obsession might be the recurring thought that something horrible has happened to a loved one, a compensating compulsion might be checking that the oven is off every five minutes. Failing to act on the compulsion results in extreme anxiety of the sort outlined above.

Post Traumatic Stress Disorder, or PTSD, is similar to GAD but occurs after an identifiable stressor (such as war, child abuse, or a traffic accident). The individual can have flashbacks to the event in question, but why some individuals develop this after trauma and others don't is unknown.

Unfortunately, the situation is seldom as clear-cut as the above syndromes suggest. Each disorder can co-exist with any of the others – GAD for instance often co-exists with social phobia and/or other phobias.

Thursday, August 9, 2007

Sugar Addiction anyone?

Avoid self-diagnosis; see your MD if you think anything might be giving cause for concern.

Possible hyperinsulinemia: in very simplistic terms this means that your pancreas over-produces or builds resistance to insulin in response to carbohydrate foods or nutritional imbalance. This can also include over-exercising and eating insufficiently to meet the needs of your body. Keep in mind that sugar addiction is not just a problem of the obese. If your goal is to manage the sugar cravings, as well as stay off the family disease path, it is imperative that you learn to eat to meet the special needs of your body. Believe it or not, this is probably the easiest part of self-management!

There are two powerful tools designed for managing psycho- biological problems such as sugar addiction: Interactive Awareness and Interactive Self-Hypnosis.

The first tool, Interactive Awareness, works as an alarm clock, it's job being to wake you up to specific moments that would benefit from your full attention, evaluation and perhaps a change of direction. Some may be obvious to you, but others may live below the surface, only known to your subconscious librarian. Keep in mind that the subconscious mind is a vast library, filled with assets with some out of conscious reach. Start to keep a food diary with times and types of food. Do the relaxation exercises and stretches to loosen the body and focus your mind in the moment. Try to capture a realistic picture of yourself as you become more in the habit of relaxation.
http://phenomenologyexistent.blogspot.com/2007/07/relax.html

Stretch in the shower and feel the water on your skin. Try and adapt these for the shower http://phenomenologyexistent.blogspot.com/2007/07/exercises.html

Once you are fully awake to the moment, you can begin to work with Interactive Self-Hypnosis. What you choose to do will depend on the moment, as well as your desired goals or outcomes. Get in a relaxed state and start to visualize --- It could be as simple as seeing yourself walking past the chocolate cake on the buffet, noticing a framed picture of yourself appearing very obese, or wearing a tee shirt with diabetes written on the front, cueing into what it feels like to be blind. If you are tired of the same old self-arguments, you might decide to use Interactive Self-Hypnosis to build up resilience from your past experiences, applying them as power stamps to your current experience. You could even choose to diminish the experience permanently, simply refusing to have this life experience at all.
Imagine yourself as you felt best in yourself and replace the poor picture of yourself with the memory 'snapshot' of the best of you. At work, being effective, at the age and place where you felt your best.

Being with food: Slow down enjoy the sensations in your mouth. Stop every so often and put down the plate and feel how you are. Once a week indulge yourself with something delicious, but see the reward as being and feeling healthier.

Women's Canadian Airforce Exercise Program XBX



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